ceesdekker.net Secrets
ceesdekker.net Secrets
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Working with solitary-molecule optical and AFM imaging and pressure-spectroscopy strategies, we look for to unravel the mechanistic aspects of the framework and dynamics of chromosomes. Our investigation interests include:
It had been only in the nineties though, when nanotechnology had Highly developed into a amount in which one molecules might be manipulated, that the 1st experimental devices started to look.
Dynamics of initiation, termination and reinitiation of DNA translocation from the motor protein EcoR124I
Given that 2000, Dekker has shifted the most crucial concentrate of his operate in direction of biophysics wherever he research the Homes of one biomolecules and cells utilizing the tools of nanotechnology. This variation of subject was pushed by his fascination for the exceptional operating of Organic molecular buildings, as well as through the prolonged-expression standpoint that many fascinating discoveries is usually expected Within this discipline.[5] Recent traces of exploration in his biophysics team are from the parts of:[six]
This yielded a breakthrough. In only a few months, we ended up capable of evaluate transport by a person one-walled carbon nanotube. Depending on small-temperature experiments by a superb PhD pupil in my team, Sander Tans (now a valued colleague and professor at Delft University of Technological innovation with the Energetic research lab at AMOLF in Amsterdam), we showed that carbon nanotubes were being real quantum wires with pretty extended (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic conduct.
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of just one wire bridging two electrodes
What distinguishes biology from chemistry is that these parts with each other make up a dwelling method. The trick of stated everyday living, I believe, lies during the interactions, the interplay of All those molecules. The big concern concerning the origin of lifetime is still unanswered. How did we at any time evolve from simple molecules to the exceptionally elaborate techniques we see currently? We have no idea. I would like to operate on These types of large, open up thoughts.’
Example (one) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim in the pore is highlighted in pink, plus a 3D rendering of the movement of the DNA rod is shown.
‘Of course, I understand men and women were stunned at some time. At the end of the nineties, Once i was in my forties, I had been Professor of Molecular Electronics and I've to admit that it had turn into a little bit bored, I didn’t find out A great deal anymore. The sphere went more into the appliance aspect, how you could integrate nanotubes into electronic circuits.
Presently, we also recognized that it should be achievable to utilize just one semiconducting carbon nanotube to create a transistor — and we set out to really make it. We stretched particular person semiconducting nanotubes throughout metallic electrodes and utilised the underlying silicon substrate as being a gate electrode, creating The essential 3-terminal layout of a industry-influence transistor (Fig.
[14] In 2005 Dekker turned involved in cees dekker Netherlands-huge discussions about Intelligent Layout, a motion that he has given that Plainly distanced himself from. Dekker advocates that science and religion will not be in opposition but can be harmonized.
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‘I am driven by question and inquiries. On a material stage I come across responses in physics, but I experience my deepest happiness with God. That faith also drives my science and how I handle men and women.